Supporting Your Boldest Breakthroughs
The Innovate Forward: Women’s Health Challenge calls on startups to accelerate solutions for perimenopause & menopause.
Tackling overlooked challenges in women’s health, we’re seeking bold ideas improve quality of life, resilience, and long-term health outcomes for women in midlife and beyond.
Open to businesses worldwide. Applicants must be legally registered entities in their respective countries. Subject to eligibility restrictions, including U.S. and international sanctions. Applications must be submitted by February 6, 2026 at 11:59 PM EST. Visit here for official rules. Void where prohibited.
Menopause Matters:
Closing the Research Gap
By 2030, 1.2 billion women worldwide will experience menopause – yet research for this critical life stage remains underfunded.
We’re advancing translational science to transform symptom relief, women’s health, and healthy aging.
About Perimenopause and Menopause
Why Menopause
Innovation Matters
By 2030, 1.2 billion women worldwide will experience menopause. Women spend nearly one-third of their lives post-menopause, facing heightened risks of metabolic ailments and other health challenges, yet this life stage has historically been underfunded and underserved in research.
- A 2022 analysis by McKinsey & Company found that only 4% of healthcare research and innovation investments focus on women’s health and just 1% target female-specific conditions beyond oncology.
- A University of Virgina study showed that symptoms often begin in women’s mid-30s, but most do not seek treatment until age 56 or later.
The need for research, innovation, and support is urgent. This challenge aims to accelerate new solutions – scientific, technological, and entrepreneurial – that address this critical gap.
“Menopause innovation is not just about symptom relief. It’s about women’s health, healthy aging, and improving quality of life for generations of women.”
Building Strong Foundations for Bold Ventures
Startup founders and translational researchers are invited to take part in the Innovate Forward Workshop Series.
The 2-part Workshop Series equips ventures with foundational tools and guidance to refine their science and sharpen their strategy.
Each workshop is led by Tufts faculty and Nestle Health Science experts, bringing scientific rigor and entrepreneurial insight to the forefront.
Workshop Schedule
Building Strong Foundations
for Bold Ventures
Startup founders and translational researchers are invited to take part in the Innovate Forward Workshop Series.
The 2-part Workshop Series equips ventures with foundational tools and guidance to refine their science and sharpen their strategy.
Each workshop is led by Tufts faculty and Nestlé Health Science experts, bringing scientific rigor and entrepreneurial insight to the forefront.
Workshop Schedule
Workshop 1
December 1, 2025
Translating Science
into Market Opportunity
- Frame scientific insights within real-world consumer and health contexts
- Map translational pathways from research to market
- Explore Nestlé’s perspective on emerging opportunities (e.g., women’s health, microbiome, cognitive health)
Workshop 2
December 3, 2025
Navigating Clinical &
Regulatory Pathways
- Prepare ventures for real-world validation and adoption
- Understand clinical evidence and scientific credibility expectations
- Navigate regulatory pathways for various product categories and health claims
- Gain insights from Nestlé’s global launch readiness experience
Workshop 3
December 3, 2025
Building Venture-Ready
Models & Strategic Narratives
- Translate innovation into a compelling and fundable venture case
- Communicate impact and differentiation to partners and investors
- Learn Nestlé’s criteria for pilots and investment readiness
- Avoid common pitfalls in translational startup storytelling
Are you a founder or researcher doing breakthrough work in perimenopause or menopause? Join us and be part of Innovate Forward 2025.
The 2025 Innovation Challenge
On World Menopause Day (October 18, 2025), applications open for the third annual Innovate Forward: Women’s Health Innovation Challenge
This global call invites early-stage startups and translational researchers to submit bold, science-driven solutions focused on:
Perimenopause & Menopause
- Symptom Relief
- Urogenital Health
- Metabolic Function
What’s at Stake
Finalists will gain:
Visibility on a global stage
One year membership to the Tufts Food & Nutrition Innovation Council with access to scientific resources and network
Six-month engagement to accelerate nutritional science with deep, multi-functional expertise from Nestlé Health Science
A one-year virtual residency with FNII for ongoing support and feedback
Who should apply?
We welcome translational research teams and emerging ventures developing innovative solutions in perimenopause & menopause, urogenital health, and metabolic health.
Focus on Perimenopause & Menopause
- Solutions focused on discovery, characterization & monitoring of biomarkers tracking menopause transition
- Symptom relief & solutions that improve quality of life during perimenopause and menopause
- Solutions that support disease prevention and risk reduction across bone, cardiovascular, cognitive, neurological, skin, musculoskeletal and immune health
- Solutions that help support fertility
- Solutions that advance mechanistic and translational research, such as biological indicators of reproductive aging, molecular & cellular pathways, immune and inflammatory pathways, longevity strategies
- Diagnostics & monitoring solutions, such as symptom tracking & coaching apps and wearable devices
- Technological or nutritional solutions, such as natural hormonal analogs, localized therapies, homeopathic remedies, microbiome-based therapies, precision nutrition and supplement-based approaches
Focus on Women’s Urogenital Health
- Solutions that focus on diagnostics & monitoring to assess changes such as vaginal atrophy, incontinence, and pelvic floor dysfunction
- Solutions that improve quality of life from relieving vaginal dryness, decreased libido and arousal, infections, inflammation, urgency/frequency, and urinary leakage
- Solutions to prevent long-term complications including recurrent UTIs, pelvic prolapse, and progression of overactive bladder.
- Therapeutic & supportive approaches, including topical & localized therapies, UTI prevention supplements, probiotics, and microbiome-based therapies
Focus on Women’s Metabolic Health
- Solutions to detect and monitor metabolic changes earlier and more accurately, including glucose & insulin regulation, cardiovascular health, bone & musculoskeletal health, and energy & cognitive function
- Solutions to manage symptoms such as fatigue, weight fluctuations, sleep disruption, brain fog, or reduced physical capacity
- Solutions to reduce long-term risks such as type 2 diabetes, cardiovascular disease, osteoporosis, and dementia by proactively targeting metabolic health.
- Technological & nutritional solutions, including novel non-prescription compounds, functional ingredients, personalized supplements, medical foods, precision nutrition, longevity molecules, microbiome-based therapies
Who should apply?
- Pre-seed and seed-stage ventures with validated prototypes or early clinical/market traction
- Series A companies ready to scale or refine their offering
- Later-stage growth companies that have launched an MVP, and are open to mentorship and collaboration with Nestlé Health Science & Tufts
Scope of Innovation
We’re seeking breakthrough solutions that:
- Support quality of life and relieve symptoms for perimenopause and menopause, urogenital health, and metabolic function
Areas of interest include vasomotor symptoms, vaginal dryness & atrophy, decreased libido & arousal, reproductive & menstrual changes, body composition & weight fluctuations, mood, sleep disruptions, brain fog, incontinence, pelvic floor dysfunction, recurrent UTIs, and pain & discomfort
- Advance technological or nutritional solutions, such as novel non-prescription compounds, natural hormonal analogs, homeopathic remedies, probiotics, microbiome-based therapies, precision nutrition, and supplement-based approaches
- Support women’s health across multiple benefit areas including bone, cardiovascular, gastrointestinal, cognitive, neurological, skin, hair, musculoskeletal, urinary, and immune health
- Enhance fertility support
- Enable discovery and characterization of biomarkers and symptom tracking for perimenopause & menopause, urogenital health, and metabolic function
Areas of interest include vaginal atrophy, bone loss, incontinence, pelvic floor dysfunction, weight gain, and glucose metabolism
- Advance translational research, such as biological indicators of reproductive aging, molecular & cellular pathways, immune and inflammatory pathways, and longevity strategies
What is the Innovate Forward: Women’s Health Challenge?
It’s a global innovation challenge designed to accelerate solutions that improve women’s health, led in partnership by Tufts Food & Nutrition Innovation Institute and Nestlé Health Science.
Who is organizing the challenge?
The challenge is co-hosted by Tufts Food & Nutrition Innovation Institute and Nestlé Health Science, with support from academic and industry partners.
What areas of women’s health are the priority for this year?
This year’s focus for Innovate Forward: Women’s Health Challenge is on perimenopause and menopause - addressing symptom relief, urogenital health, and metabolic resilience.
Why should I apply to the Innovation Challenge?
You should apply to the Innovation Challenge for the following reasons:
- Visibility & Recognition - Showcase your work on a global stage, backed by Tufts Food & Nutrition Innovation Institute and Nestlé Health Science.
- Mentorship - Winners receive direct mentorship from FNII and Nestlé Health Science experts on regulatory pathways, product development, and scaling strategies.
- Partnership Opportunities - Explore collaborations with world-class academic and industry partners committed to advancing perimenopause and menopause care.
- Community - Join a network of innovators and gain recognition for addressing one of the most urgent and underserved areas of women’s health.
Where can I find the Rules & Eligibility to download?
You can download the rules & eligibility here.
Who can apply to the challenge?
Entrepreneurs, researchers, startups, and students working on women’s health solutions are welcome.
Do I need to have a fully developed product or is an early-stage idea acceptable?
Both early-stage ideas and developed solutions are eligible. This includes:
- Pre-seed and seed-stage ventures with validated prototypes or early clinical/market traction.
- Series A companies ready to scale or refine their offering.
- Later-stage growth companies that have launched an MVP, and open to mentorship and collaboration with Nestlé Health Science & Tufts.
What level of technology or scientific readiness is required?
Solutions should demonstrate a credible scientific basis and some level of early validation. This may include:
- Preclinical or clinical evidence
- Peer-reviewed data
- Proof-of-concept or early prototype results
The goal is to ensure that innovations have a sound foundation and can realistically benefit from the mentorship, resources, and networks provided by Tufts and Nestlé.
Are international applicants eligible?
Yes, applications are welcome from around the world. Exclusions apply. See official rules for details.
How do I apply?
Complete the online application form available on the challenge website.
What information do I need to include in my application?
You’ll be asked for a short description of your innovation, the problem it addresses, your target audience, and your development stage.
Is there an application fee?
No, applying to the challenge is free.
What must the pitch deck include?
The pitch deck should address unmet need, your solution and differentiation, competitive advantage, scientific basis, key data, business case, IP overview, team expertise, and a roadmap for growth.
What are the key deadlines I need to know?
Applications must be submitted between October 18, 2025 and February 6, 2026.
Can I submit multiple entries?
No, each applicant may only submit one entry.
Who are the judges?
The Innovate Forward Committee, made up of experts in science, medicine, and commercialization from the Tufts and Nestlé Health Science teams.
What criteria will judges use to evaluate proposals?
Applications are judged on: Innovation, Impact, Fit with focus areas, Intellectual property, Business model, Team qualifications, and Quality of presentation.
When will the finalists be selected?
Finalists will be selected between February and March 2026 and will pitch virtually. Award recipients will be announced early 2026.
What do winners or finalists receive?
- A 6-month virtual residency with Innovate Forward: Tufts and Nestlé experts, including mentorship and technical guidance.
- A 1-year virtual residency with Tufts’ Food & Nutrition Innovation Council, providing access to a global network
Will Nestlé have rights to my idea?
No, applicants retain IP ownership, but Award Recipients grant Nestlé a short option period of 3 months to negotiate for further development or commercialization.
Will my application be confidential?
Applications and pitch presentations are non-confidential. Applicants should not include proprietary or trade secret information.
Is travel required?
No, the program is designed to be virtual. If you’re selected as a finalist, you may have to present virtually
Who covers expenses?
Applicants are responsible for their own expenses related to preparing and presenting
Who do I contact for questions?
Email the challenge team at fnii@tufts.edu
Keto Kare: A Science-Backed, Plant-Based Nutritional Shake
Keto Kare is a nutritional drink specifically formulated to support individuals managing their carbohydrate intake on a ketogenic diet, providing essential nutrients while aligning with the principles of ketosis. The development of Keto Kare was driven by the objective of offering a science-backed, plant-based nutritional shake that can be utilized by individuals who have specific nutritional goals and follow a ketogenic diet.
Mauricio Moel, co-founder of Keto Kare, shared his gratitude for being selected as a winner in the startup challenge. He stated, “With the invaluable support and mentorship of experts from Nestlé Health Science and Tufts University, we look forward to further developing and expanding Keto Kare. Our aim is to contribute to the advancement of ketogenic nutrition innovation and make a positive impact on the lives of individuals seeking to support their health.”
Superfrau: A Functional and Sustainable Beverage
Superfrau is a sparkling functional beverage that utilizes upcycled whey to create a drink offering protein, B-Vitamins and electrolytes. The upcycled whey used in Superfrau is sourced from yogurt production, which would typically be discarded or used as feedstock.
Melissa Martinelli, the visionary founder of Superfrau, expressed her excitement upon winning the challenge. She emphasized, “This achievement represents a remarkable milestone for Superfrau. With the invaluable guidance and expertise of Nestlé Health Science and Tufts University, we are eager to broaden our impact and offer consumers a delightful and nourishing beverage that empowers them to make health-conscious food choices while also helping reduce waste.”
KRESKO RNA 2024
By unlocking the potential of dietary RNAs—bioactive compounds naturally found in fresh foods that play a crucial role in cellular health—Kresko RNAtech has demonstrated their exceptional ability to discover and leverage dietary RNAs for use as functional ingredients across a diverse array of products. Their innovative technology enables the discovery and stabilization of RNA compounds that can be incorporated into food and supplements, effectively addressing various health needs and supporting consumer demands.
“Kresko RNAtech emerged as an outstanding applicant and we’re thrilled to name their business as the winner of our annual Innovation Challenge, now in its second year,” said Rania Abou Samra, Global Head of Technology and Product Development for Nestlé Health Science. “The team’s innovative approach to dietary RNAs complements our commitment to advancing nutritional science and developing solutions that support overall health and wellness. We’re excited to continue supporting their mission.”
As the selected winner, Kresko RNAtech will receive in-depth mentorship, strategy guidance, and technical support from experts at Nestlé Health Science and Tufts University, in addition to a one-year membership on the Institute’s Food & Nutrition Innovation Council with access to its network.
“We are excited to welcome Kresko RNAtech to the Food & Nutrition Innovation Council as the winner of this year’s Innovate Forward Challenge,” added Katie Stebbins, Executive Director of the Food & Nutrition Innovation Institute. “We are equally excited to collaborate with Nestlé Health Science to support Kresko RNAtech as they continue to add value to their science and product offerings.”
Apply to Innovate Forward 2025
Applications open October 18, 2025 on World Menopause Day.
If you’re a startup or research-driven venture developing innovative solutions in the menopause transition, urogenital health, or metabolic resilience, we want to hear from you.
Eligibility
- Early- and growth-stage startups in women’s health & aging
- Translational research teams with commercialization potential
- Global applicants welcome
Timeline
- October 18, 2025: Applications Open
- February 6, 2026: Applications Close.
- Early 2026: Finalist selection and Winners announced.
About Tufts FNII
Nestlé Health Science, a leader in the science of nutrition, is a globally managed business unit of Nestlé. We are committed to redefining the management of health, offering an extensive portfolio of science-based consumer health, medical nutrition, pharmaceutical therapies, and vitamin and supplement brands. Our extensive research network provides the foundation for products that empower healthier lives through nutrition. Headquartered in Switzerland, we have more than 12,000 employees around the world, with products available in more than 140 countries. For more information, please visit
About Nestlé Health Science
Nestlé Health Science, a leader in the science of nutrition, is a globally managed business unit of Nestlé. We are committed to redefining the management of health, offering an extensive portfolio of science-based consumer health, medical nutrition, pharmaceutical therapies, and vitamin and supplement brands. Our extensive research network provides the foundation for products that empower healthier lives through nutrition. Headquartered in Switzerland, we have more than 12,000 employees around the world, with products available in more than 140 countries. For more information, please visit
Innovate Forward is a global innovation challenge created through a partnership between the Tufts Food & Nutrition Innovation Institute and Nestlé Health Science. Together, we are accelerating solutions that advance women’s health by bridging cutting-edge research, entrepreneurship, and translational science. Our mission is to spotlight bold ideas and empower innovators developing new approaches to women’s health, from longevity to menopause.
About Tufts FNII
The Food and Nutrition Innovation Institute (FNII) aims to foster a robust, science-driven ecosystem of food, agricultural, and wellness innovation and entrepreneurship for a healthier, equitable, and sustainable food system.
FNII is hosted by the Friedman School, but brings together many schools at Tufts to seek out and foster innovation and entrepreneurship in these areas.
About Nestlé Health Science
Nestlé Health Science, a leader in the science of nutrition, is a globally managed business unit of Nestlé.
We are committed to redefining the management of health, offering an extensive portfolio of science-based consumer health, medical nutrition, pharmaceutical therapies, and vitamin and supplement brands.
PARTNER WITH US
Innovation happens when great ideas meet strong partnerships. The Innovate Forward team at Tufts Food & Nutrition Innovation Institute and Nestlé Health Science welcomes collaborators ready to drive solutions in women’s health, healthy aging, and the menopause transition.
We’re also seeking researchers and startups to spotlight – sharing stories of bold innovation and connecting them with our global community.
Let’s connect and explore how we can work together.
Please reach out to us at FNII@Tufts.edu or schedule an introductory meeting with our team directly with a link below.